diff --git a/Wox.Core/UserSettings/UserSettingStorage.cs b/Wox.Core/UserSettings/UserSettingStorage.cs
index c01538e623..632aaaa507 100644
--- a/Wox.Core/UserSettings/UserSettingStorage.cs
+++ b/Wox.Core/UserSettings/UserSettingStorage.cs
@@ -86,6 +86,9 @@ namespace Wox.Core.UserSettings
         [JsonProperty]
         public bool RememberLastLaunchLocation { get; set; }
 
+        [JsonProperty]
+        public bool IgnoreHotkeysOnFullscreen { get; set; }
+
         [JsonProperty]
         public string ProxyServer { get; set; }
 
diff --git a/Wox/Helper/WindowIntelopHelper.cs b/Wox/Helper/WindowIntelopHelper.cs
index 2e5179b7b4..feccd8f6a4 100644
--- a/Wox/Helper/WindowIntelopHelper.cs
+++ b/Wox/Helper/WindowIntelopHelper.cs
@@ -1,9 +1,9 @@
 using System;
-using System.Collections.Generic;
-using System.Linq;
-using System.Text;
+using System.Drawing;
 using System.Runtime.InteropServices;
 using System.Windows;
+using System.Windows.Forms;
+using System.Windows.Interop;
 
 namespace Wox.Helper
 {
@@ -11,6 +11,25 @@ namespace Wox.Helper
     {
         private const int GWL_STYLE = -16; //WPF's Message code for Title Bar's Style 
         private const int WS_SYSMENU = 0x80000; //WPF's Message code for System Menu
+        private static IntPtr _hwnd_shell;
+        private static IntPtr _hwnd_desktop;
+        
+        //Accessors for shell and desktop handlers
+        //Will set the variables once and then will return them
+        private static IntPtr HWND_SHELL
+        {
+            get
+            {
+                return _hwnd_shell != null ? _hwnd_shell : _hwnd_shell = GetShellWindow();
+            }
+        }
+        private static IntPtr HWND_DESKTOP
+        {
+            get
+            {
+                return _hwnd_desktop != null ? _hwnd_desktop : _hwnd_desktop = GetDesktopWindow();
+            }
+        }
 
         [DllImport("user32.dll", SetLastError = true)]
         private static extern int GetWindowLong(IntPtr hWnd, int nIndex);
@@ -18,14 +37,56 @@ namespace Wox.Helper
         [DllImport("user32.dll")]
         private static extern int SetWindowLong(IntPtr hWnd, int nIndex, int dwNewLong);
 
+        [DllImport("user32.dll")]
+        private static extern IntPtr GetForegroundWindow();
+
+        [DllImport("user32.dll")]
+        private static extern IntPtr GetDesktopWindow();
+
+        [DllImport("user32.dll")]
+        private static extern IntPtr GetShellWindow();
+
+        [DllImport("user32.dll", SetLastError = true)]
+        private static extern int GetWindowRect(IntPtr hwnd, out RECT rc);
+
+        public static bool IsWindowFullscreen()
+        {
+            RECT foreWinBounds;
+            Rectangle screenBounds;
+            var hWnd = GetForegroundWindow();
+            if (!hWnd.Equals(IntPtr.Zero))
+            {
+                if (!(hWnd.Equals(HWND_DESKTOP) || hWnd.Equals(HWND_SHELL)))
+                {
+                    GetWindowRect(hWnd, out foreWinBounds);
+                    screenBounds = Screen.FromHandle(hWnd).Bounds;
+                    if ((foreWinBounds.Bottom - foreWinBounds.Top) == screenBounds.Height && (foreWinBounds.Right - foreWinBounds.Left) == screenBounds.Width)
+                    {
+                        return true;
+                    }
+                }
+            }
+
+            return false;
+        }
+
         /// <summary>
-        /// disable windows toolbar's control box
-        /// this will also disable system menu with Alt+Space hotkey
+        ///     disable windows toolbar's control box
+        ///     this will also disable system menu with Alt+Space hotkey
         /// </summary>
         public static void DisableControlBox(Window win)
         {
-            var hwnd = new System.Windows.Interop.WindowInteropHelper(win).Handle;
+            var hwnd = new WindowInteropHelper(win).Handle;
             SetWindowLong(hwnd, GWL_STYLE, GetWindowLong(hwnd, GWL_STYLE) & ~WS_SYSMENU);
         }
+
+        [StructLayout(LayoutKind.Sequential)]
+        public struct RECT
+        {
+            public int Left;
+            public int Top;
+            public int Right;
+            public int Bottom;
+        }
     }
-}
+}
\ No newline at end of file
diff --git a/Wox/Languages/en.xaml b/Wox/Languages/en.xaml
index 3d0946aa3b..fe252ebb98 100644
--- a/Wox/Languages/en.xaml
+++ b/Wox/Languages/en.xaml
@@ -23,6 +23,7 @@
     <system:String x:Key="rememberLastLocation">Remember last launch location</system:String>
     <system:String x:Key="language">Language</system:String>
     <system:String x:Key="maxShowResults">Maximum show results</system:String>
+    <system:String x:Key="ignoreHotkeysOnFullscreen">Ignore hotkeys if window is fullscreen</system:String>
     
     <!--Setting Plugin-->
     <system:String x:Key="plugin">Plugin</system:String>
diff --git a/Wox/Languages/ru.xaml b/Wox/Languages/ru.xaml
index efb3d9521a..e09aa9bc73 100644
--- a/Wox/Languages/ru.xaml
+++ b/Wox/Languages/ru.xaml
@@ -23,6 +23,7 @@
     <system:String x:Key="rememberLastLocation">Запомнить последнее место запуска</system:String>
     <system:String x:Key="language">Язык</system:String>
     <system:String x:Key="maxShowResults">Максимальное количество результатов</system:String>
+    <system:String x:Key="ignoreHotkeysOnFullscreen">Игнорировать горячие клавиши, если окно в полноэкранном режиме</system:String>
     
     <!--Setting Plugin-->
     <system:String x:Key="plugin">Плагины</system:String>
diff --git a/Wox/Languages/zh-cn.xaml b/Wox/Languages/zh-cn.xaml
index e2ab87c4b2..7e00547603 100644
--- a/Wox/Languages/zh-cn.xaml
+++ b/Wox/Languages/zh-cn.xaml
@@ -23,6 +23,7 @@
     <system:String x:Key="rememberLastLocation">记住上次启动位置</system:String>
     <system:String x:Key="language">语言</system:String>
     <system:String x:Key="maxShowResults">最大结果显示个数</system:String>
+    <system:String x:Key="ignoreHotkeysOnFullscreen">Ignore hotkeys if foreground window is TopMost</system:String>
 
     <!--设置，插件-->
     <system:String x:Key="plugin">插件</system:String>
diff --git a/Wox/Languages/zh-tw.xaml b/Wox/Languages/zh-tw.xaml
index c0fd4a63b5..0f1ab8f9c4 100644
--- a/Wox/Languages/zh-tw.xaml
+++ b/Wox/Languages/zh-tw.xaml
@@ -23,6 +23,7 @@
     <system:String x:Key="rememberLastLocation">记住上次启动位置</system:String>
     <system:String x:Key="language">語言</system:String>
     <system:String x:Key="maxShowResults">最大結果顯示個數</system:String>
+    <system:String x:Key="ignoreHotkeysOnFullscreen">Ignore hotkeys if foreground window is TopMost</system:String>
 
     <!--設置，插件-->
     <system:String x:Key="plugin">插件</system:String>
diff --git a/Wox/MainWindow.xaml.cs b/Wox/MainWindow.xaml.cs
index 35e7df4965..9e305ff40c 100644
--- a/Wox/MainWindow.xaml.cs
+++ b/Wox/MainWindow.xaml.cs
@@ -356,6 +356,20 @@ namespace Wox
             }
         }
 
+        /// <summary>
+        /// Checks if Wox should ignore any hotkeys
+        /// </summary>
+        /// <returns></returns>
+        private bool ShouldIgnoreHotkeys()
+        {
+            //double if to omit calling win32 function
+            if (UserSettingStorage.Instance.IgnoreHotkeysOnFullscreen)
+                if(WindowIntelopHelper.IsWindowFullscreen())
+                    return true;
+
+            return false;
+        }
+
         private void SetCustomPluginHotkey()
         {
             if (UserSettingStorage.Instance.CustomPluginHotkeys == null) return;
@@ -364,6 +378,7 @@ namespace Wox
                 CustomPluginHotkey hotkey1 = hotkey;
                 SetHotkey(hotkey.Hotkey, delegate
                 {
+                    if (ShouldIgnoreHotkeys()) return;
                     ShowApp();
                     ChangeQuery(hotkey1.ActionKeyword, true);
                 });
@@ -372,6 +387,7 @@ namespace Wox
 
         private void OnHotkey(object sender, HotkeyEventArgs e)
         {
+            if (ShouldIgnoreHotkeys()) return;
             ToggleWox();
             e.Handled = true;
         }
diff --git a/Wox/SettingWindow.xaml b/Wox/SettingWindow.xaml
index ac40627a54..b322cf16d5 100644
--- a/Wox/SettingWindow.xaml
+++ b/Wox/SettingWindow.xaml
@@ -35,6 +35,9 @@
                 <CheckBox x:Name="cbRememberLastLocation" Margin="10">
                     <TextBlock Text="{DynamicResource rememberLastLocation}" ></TextBlock>
                 </CheckBox>
+                <CheckBox x:Name="cbIgnoreHotkeysOnFullscreen" Margin="10">
+                    <TextBlock Text="{DynamicResource ignoreHotkeysOnFullscreen}" ></TextBlock>
+                </CheckBox>
                 <StackPanel Margin="10" Orientation="Horizontal">
                     <TextBlock  Text="{DynamicResource language}"></TextBlock>
                     <ComboBox Margin="10 0 0 0" Width="120" x:Name="cbLanguages" />
diff --git a/Wox/SettingWindow.xaml.cs b/Wox/SettingWindow.xaml.cs
index 7ede741c6a..5520b4c534 100644
--- a/Wox/SettingWindow.xaml.cs
+++ b/Wox/SettingWindow.xaml.cs
@@ -49,7 +49,6 @@ namespace Wox
         private void Setting_Loaded(object sender, RoutedEventArgs ev)
         {
             #region General
-
             cbHideWhenDeactive.Checked += (o, e) =>
             {
                 UserSettingStorage.Instance.HideWhenDeactive = true;
@@ -86,6 +85,20 @@ namespace Wox
                 UserSettingStorage.Instance.Save();
             };
 
+            cbIgnoreHotkeysOnFullscreen.Checked += (o, e) =>
+            {
+                UserSettingStorage.Instance.IgnoreHotkeysOnFullscreen = true;
+                UserSettingStorage.Instance.Save();
+            };
+
+
+            cbIgnoreHotkeysOnFullscreen.Unchecked += (o, e) =>
+            {
+                UserSettingStorage.Instance.IgnoreHotkeysOnFullscreen = false;
+                UserSettingStorage.Instance.Save();
+            };
+
+
             cbStartWithWindows.IsChecked = CheckApplicationIsStartupWithWindow();
             comboMaxResultsToShow.SelectionChanged += (o, e) =>
             {
@@ -97,6 +110,7 @@ namespace Wox
             cbHideWhenDeactive.IsChecked = UserSettingStorage.Instance.HideWhenDeactive;
             cbDontPromptUpdateMsg.IsChecked = UserSettingStorage.Instance.DontPromptUpdateMsg;
             cbRememberLastLocation.IsChecked = UserSettingStorage.Instance.RememberLastLaunchLocation;
+            cbIgnoreHotkeysOnFullscreen.IsChecked = UserSettingStorage.Instance.IgnoreHotkeysOnFullscreen;
 
             LoadLanguages();
             comboMaxResultsToShow.ItemsSource = Enumerable.Range(2, 16);