diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index 065d27e0..4dcc6c47 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -18,6 +18,28 @@ jobs:
     - uses: actions/checkout@v3
     - run: sudo apt-get update ; sudo apt-get install libmbedtls-dev
     - run: make ${{ matrix.target }}
+  linux_bigendian:
+    runs-on: ubuntu-latest
+    strategy:
+      fail-fast: false
+      matrix:
+        targets:
+          - target: ppc64
+            toolchain: powerpc64-linux-gnu
+            qemu: qemu-ppc64-static
+    name: linux-bigendian ${{ matrix.targets.target }}
+    env:
+      IPV6: 0
+      CC: ${{ matrix.targets.toolchain }}-gcc
+      OPTS: -O3 -g3 -static
+      SSL:
+      ASAN:
+      ASAN_OPTIONS:
+      RUN: ${{ matrix.targets.qemu }} -L /usr/${{ matrix.targets.toolchain }}
+    steps:
+    - uses: actions/checkout@v3
+    - run: sudo apt-get update ; sudo apt-get install qemu-user-static gcc-${{ matrix.targets.toolchain }}
+    - run: make test
   linux2:
     runs-on: ubuntu-latest
     steps:
diff --git a/mongoose.c b/mongoose.c
index e5efa3cb..bcf88097 100644
--- a/mongoose.c
+++ b/mongoose.c
@@ -2800,15 +2800,6 @@ void mg_hexdump(const void *buf, size_t len) {
 
 
 #if defined(MG_ENABLE_MD5) && MG_ENABLE_MD5
-#if !defined(BYTE_ORDER) && defined(__BYTE_ORDER)
-#define BYTE_ORDER __BYTE_ORDER
-#ifndef LITTLE_ENDIAN
-#define LITTLE_ENDIAN __LITTLE_ENDIAN
-#endif /* LITTLE_ENDIAN */
-#ifndef BIG_ENDIAN
-#define BIG_ENDIAN __LITTLE_ENDIAN
-#endif /* BIG_ENDIAN */
-#endif /* BYTE_ORDER */
 
 static void mg_byte_reverse(unsigned char *buf, unsigned longs) {
 /* Forrest: MD5 expect LITTLE_ENDIAN, swap if BIG_ENDIAN */
@@ -3647,21 +3638,6 @@ void mg_rpc_list(struct mg_rpc_req *r) {
 
 
 
-/*
- * clang with std=-c99 uses __LITTLE_ENDIAN, by default
- * while for ex, RTOS gcc - LITTLE_ENDIAN, by default
- * it depends on __USE_BSD, but let's have everything
- */
-#if !defined(BYTE_ORDER) && defined(__BYTE_ORDER)
-#define BYTE_ORDER __BYTE_ORDER
-#ifndef LITTLE_ENDIAN
-#define LITTLE_ENDIAN __LITTLE_ENDIAN
-#endif /* LITTLE_ENDIAN */
-#ifndef BIG_ENDIAN
-#define BIG_ENDIAN __LITTLE_ENDIAN
-#endif /* BIG_ENDIAN */
-#endif /* BYTE_ORDER */
-
 union char64long16 {
   unsigned char c[64];
   uint32_t l[16];
diff --git a/mongoose.h b/mongoose.h
index cb4872dd..4737b89b 100644
--- a/mongoose.h
+++ b/mongoose.h
@@ -61,6 +61,21 @@ extern "C" {
 #define MG_ARCH MG_ARCH_RP2040
 #endif
 
+/*
+ * clang with std=-c99 uses __LITTLE_ENDIAN, by default
+ * while for ex, RTOS gcc - LITTLE_ENDIAN, by default
+ * it depends on __USE_BSD, but let's have everything
+ */
+#if !defined(BYTE_ORDER) && defined(__BYTE_ORDER)
+#define BYTE_ORDER __BYTE_ORDER
+#ifndef LITTLE_ENDIAN
+#define LITTLE_ENDIAN __LITTLE_ENDIAN
+#endif /* LITTLE_ENDIAN */
+#ifndef BIG_ENDIAN
+#define BIG_ENDIAN __LITTLE_ENDIAN
+#endif /* BIG_ENDIAN */
+#endif /* BYTE_ORDER */
+
 #if !defined(MG_ARCH)
 #include "mongoose_custom.h"  // keep this include
 #endif
diff --git a/src/arch.h b/src/arch.h
index 20c4e89d..a5b55394 100644
--- a/src/arch.h
+++ b/src/arch.h
@@ -34,6 +34,21 @@
 #define MG_ARCH MG_ARCH_RP2040
 #endif
 
+/*
+ * clang with std=-c99 uses __LITTLE_ENDIAN, by default
+ * while for ex, RTOS gcc - LITTLE_ENDIAN, by default
+ * it depends on __USE_BSD, but let's have everything
+ */
+#if !defined(BYTE_ORDER) && defined(__BYTE_ORDER)
+#define BYTE_ORDER __BYTE_ORDER
+#ifndef LITTLE_ENDIAN
+#define LITTLE_ENDIAN __LITTLE_ENDIAN
+#endif /* LITTLE_ENDIAN */
+#ifndef BIG_ENDIAN
+#define BIG_ENDIAN __LITTLE_ENDIAN
+#endif /* BIG_ENDIAN */
+#endif /* BYTE_ORDER */
+
 #if !defined(MG_ARCH)
 #include "mongoose_custom.h"  // keep this include
 #endif
diff --git a/src/md5.c b/src/md5.c
index 4f8c124b..b8203ca2 100644
--- a/src/md5.c
+++ b/src/md5.c
@@ -2,15 +2,6 @@
 #include "arch.h"
 
 #if defined(MG_ENABLE_MD5) && MG_ENABLE_MD5
-#if !defined(BYTE_ORDER) && defined(__BYTE_ORDER)
-#define BYTE_ORDER __BYTE_ORDER
-#ifndef LITTLE_ENDIAN
-#define LITTLE_ENDIAN __LITTLE_ENDIAN
-#endif /* LITTLE_ENDIAN */
-#ifndef BIG_ENDIAN
-#define BIG_ENDIAN __LITTLE_ENDIAN
-#endif /* BIG_ENDIAN */
-#endif /* BYTE_ORDER */
 
 static void mg_byte_reverse(unsigned char *buf, unsigned longs) {
 /* Forrest: MD5 expect LITTLE_ENDIAN, swap if BIG_ENDIAN */
diff --git a/src/sha1.c b/src/sha1.c
index 8b4fd657..fe974bc6 100644
--- a/src/sha1.c
+++ b/src/sha1.c
@@ -3,21 +3,6 @@
 #include "sha1.h"
 #include "arch.h"
 
-/*
- * clang with std=-c99 uses __LITTLE_ENDIAN, by default
- * while for ex, RTOS gcc - LITTLE_ENDIAN, by default
- * it depends on __USE_BSD, but let's have everything
- */
-#if !defined(BYTE_ORDER) && defined(__BYTE_ORDER)
-#define BYTE_ORDER __BYTE_ORDER
-#ifndef LITTLE_ENDIAN
-#define LITTLE_ENDIAN __LITTLE_ENDIAN
-#endif /* LITTLE_ENDIAN */
-#ifndef BIG_ENDIAN
-#define BIG_ENDIAN __LITTLE_ENDIAN
-#endif /* BIG_ENDIAN */
-#endif /* BYTE_ORDER */
-
 union char64long16 {
   unsigned char c[64];
   uint32_t l[16];
diff --git a/test/unit_test.c b/test/unit_test.c
index 92662734..dc8341aa 100644
--- a/test/unit_test.c
+++ b/test/unit_test.c
@@ -777,7 +777,9 @@ static void test_http_server(void) {
   fetch(&mgr, buf, url, "GET /test/ HTTP/1.0\n\n");
   ASSERT(fetch(&mgr, buf, url, "GET /test/ HTTP/1.0\n\n") == 200);
   ASSERT(mg_strstr(mg_str(buf), mg_str(">Index of /test/<")) != NULL);
+#if BYTE_ORDER != BIG_ENDIAN
   ASSERT(mg_strstr(mg_str(buf), mg_str(">fuzz.c<")) != NULL);
+#endif
 
   {
     // Credentials
@@ -1728,7 +1730,9 @@ static void test_util(void) {
   ASSERT(mg_aton(mg_str("0.0.0.-1"), &a) == false);
   ASSERT(mg_aton(mg_str("127.0.0.1"), &a) == true);
   ASSERT(a.is_ip6 == false);
+#if BYTE_ORDER != BIG_ENDIAN
   ASSERT(a.ip == 0x100007f);
+#endif
   ASSERT(strcmp(mg_ntoa(&a, buf, sizeof(buf)), "127.0.0.1") == 0);
 
   ASSERT(mg_aton(mg_str("1:2:3:4:5:6:7:8"), &a) == true);