diff --git a/src/http/modules/ngx_http_proxy_module.c b/src/http/modules/ngx_http_proxy_module.c
index 6bbbfaebf..efb4bed8e 100644
--- a/src/http/modules/ngx_http_proxy_module.c
+++ b/src/http/modules/ngx_http_proxy_module.c
@@ -1095,7 +1095,7 @@ ngx_http_proxy_create_key(ngx_http_request_t *r)
 
     loc_len = (r->valid_location && ctx->vars.uri.len) ? plcf->location.len : 0;
 
-    if (r->quoted_uri || r->internal) {
+    if (r->quoted_uri || r->space_in_uri || r->internal) {
         escape = 2 * ngx_escape_uri(NULL, r->uri.data + loc_len,
                                     r->uri.len - loc_len, NGX_ESCAPE_URI);
     } else {