diff --git a/setup.py b/setup.py
index 61b3266..4c2cfb4 100644
--- a/setup.py
+++ b/setup.py
@@ -1153,6 +1153,7 @@ def detect_readline_curses(self):
             self.add(Extension('readline', ['readline.c'],
                                library_dirs=['/usr/lib/termcap'],
                                extra_link_args=readline_extra_link_args,
+                               runtime_library_dirs=self.lib_dirs,
                                libraries=readline_libs))
         else:
             self.missing.append('readline')
@@ -1189,6 +1190,7 @@ def detect_readline_curses(self):
                                extra_compile_args=['-DPy_BUILD_CORE_MODULE'],
                                include_dirs=curses_includes,
                                define_macros=curses_defines,
+                               runtime_library_dirs=self.lib_dirs,
                                libraries=curses_libs))
         elif curses_library == 'curses' and not MACOS:
                 # OSX has an old Berkeley curses, not good enough for
@@ -1203,6 +1205,7 @@ def detect_readline_curses(self):
             self.add(Extension('_curses', ['_cursesmodule.c'],
                                extra_compile_args=['-DPy_BUILD_CORE_MODULE'],
                                define_macros=curses_defines,
+                               runtime_library_dirs=self.lib_dirs,
                                libraries=curses_libs))
         else:
             curses_enabled = False
@@ -1216,6 +1219,7 @@ def detect_readline_curses(self):
             self.add(Extension('_curses_panel', ['_curses_panel.c'],
                            include_dirs=curses_includes,
                            define_macros=curses_defines,
+                           runtime_library_dirs=self.lib_dirs,
                            libraries=[panel_library, *curses_libs]))
         elif not skip_curses_panel:
             self.missing.append('_curses_panel')
@@ -1234,7 +1238,7 @@ def detect_crypt(self):
         else:
             libs = []
 
-        self.add(Extension('_crypt', ['_cryptmodule.c'], libraries=libs))
+        self.add(Extension('_crypt', ['_cryptmodule.c'], runtime_library_dirs=self.lib_dirs, libraries=libs))
 
     def detect_socket(self):
         # socket(2)
@@ -1525,6 +1529,7 @@ class db_found(Exception): pass
                                            libraries=dblibs)
                         break
             if dbmext is not None:
+                dbmext.runtime_library_dirs = self.lib_dirs
                 self.add(dbmext)
             else:
                 self.missing.append('_dbm')
@@ -1533,6 +1538,7 @@ class db_found(Exception): pass
         if ('gdbm' in dbm_order and
             self.compiler.find_library_file(self.lib_dirs, 'gdbm')):
             self.add(Extension('_gdbm', ['_gdbmmodule.c'],
+                               runtime_library_dirs=self.lib_dirs,
                                libraries=['gdbm']))
         else:
             self.missing.append('_gdbm')
@@ -1645,6 +1651,7 @@ def detect_sqlite(self):
                                define_macros=sqlite_defines,
                                include_dirs=include_dirs,
                                library_dirs=sqlite_libdir,
+                               runtime_library_dirs=self.lib_dirs,
                                extra_link_args=sqlite_extra_link_args,
                                libraries=["sqlite3",]))
         else:
@@ -1710,6 +1717,7 @@ def detect_compress_exts(self):
                         zlib_extra_link_args = ()
                     self.add(Extension('zlib', ['zlibmodule.c'],
                                        libraries=['z'],
+                                       runtime_library_dirs=self.lib_dirs,
                                        extra_link_args=zlib_extra_link_args))
                     have_zlib = True
                 else:
@@ -1732,6 +1740,7 @@ def detect_compress_exts(self):
         self.add(Extension('binascii', ['binascii.c'],
                            extra_compile_args=extra_compile_args,
                            libraries=libraries,
+                           runtime_library_dirs=self.lib_dirs,
                            extra_link_args=extra_link_args))
 
         # Gustavo Niemeyer's bz2 module.
@@ -1742,6 +1751,7 @@ def detect_compress_exts(self):
                 bz2_extra_link_args = ()
             self.add(Extension('_bz2', ['_bz2module.c'],
                                libraries=['bz2'],
+                               runtime_library_dirs=self.lib_dirs,
                                extra_link_args=bz2_extra_link_args))
         elif (self.compiler.find_library_file(self.lib_dirs, 'bz2d')):
             if MACOS:
@@ -1750,6 +1760,7 @@ def detect_compress_exts(self):
                 bz2_extra_link_args = ()
             self.add(Extension('_bz2', ['_bz2module.c'],
                                libraries=['bz2d'],
+                               runtime_library_dirs=self.lib_dirs,
                                extra_link_args=bz2_extra_link_args))
         else:
             self.missing.append('_bz2')
@@ -1757,6 +1768,7 @@ def detect_compress_exts(self):
         # LZMA compression support.
         if self.compiler.find_library_file(self.lib_dirs, 'lzma'):
             self.add(Extension('_lzma', ['_lzmamodule.c'],
+                               runtime_library_dirs=self.lib_dirs,
                                libraries=['lzma']))
         else:
             self.missing.append('_lzma')
@@ -1819,6 +1831,7 @@ def detect_expat_elementtree(self):
                            extra_compile_args=extra_compile_args,
                            include_dirs=expat_inc,
                            libraries=expat_lib,
+                           runtime_library_dirs=self.lib_dirs,
                            sources=['pyexpat.c'] + expat_sources,
                            depends=expat_depends))
 
@@ -1831,6 +1844,7 @@ def detect_expat_elementtree(self):
                                define_macros=define_macros,
                                include_dirs=expat_inc,
                                libraries=expat_lib,
+                               runtime_library_dirs=self.lib_dirs,
                                sources=['_elementtree.c'],
                                depends=['pyexpat.c', *expat_sources,
                                         *expat_depends]))
@@ -1883,6 +1897,7 @@ def detect_uuid(self):
             else:
                 uuid_libs = []
             self.add(Extension('_uuid', ['_uuidmodule.c'],
+                               runtime_library_dirs=self.lib_dirs,
                                libraries=uuid_libs))
         else:
             self.missing.append('_uuid')
@@ -2319,6 +2334,7 @@ def detect_ctypes(self):
                 ext.extra_compile_args.append("-DHAVE_FFI_CLOSURE_ALLOC=1")
 
             ext.include_dirs.append(ffi_inc)
+            ext.runtime_library_dirs = self.lib_dirs
             ext.libraries.append(ffi_lib)
             self.use_system_libffi = True
 
@@ -2485,7 +2501,7 @@ def split_var(name, sep):
             include_dirs=openssl_includes,
             library_dirs=openssl_libdirs,
             libraries=openssl_libs,
-            runtime_library_dirs=runtime_library_dirs,
+            runtime_library_dirs=self.lib_dirs,
         )
 
         # This static linking is NOT OFFICIALLY SUPPORTED.
@@ -2639,6 +2655,7 @@ def detect_nis(self):
         self.add(Extension('nis', ['nismodule.c'],
                            libraries=libs,
                            library_dirs=library_dirs,
+                           runtime_library_dirs=self.lib_dirs,
                            include_dirs=includes_dirs))