diff --git a/PCbuild/pythoncore.vcxproj b/PCbuild/pythoncore.vcxproj
index ca83b82d8a0fe..b925a26a96e5e 100644
--- a/PCbuild/pythoncore.vcxproj
+++ b/PCbuild/pythoncore.vcxproj
@@ -104,6 +104,10 @@
       <AdditionalIncludeDirectories Condition="$(IncludeExternals)">$(zlibDir);%(AdditionalIncludeDirectories)</AdditionalIncludeDirectories>
       <PreprocessorDefinitions>_USRDLL;Py_BUILD_CORE;Py_BUILD_CORE_BUILTIN;MS_DLL_ID="$(SysWinVer)";%(PreprocessorDefinitions)</PreprocessorDefinitions>
       <PreprocessorDefinitions Condition="$(IncludeExternals)">_Py_HAVE_ZLIB;%(PreprocessorDefinitions)</PreprocessorDefinitions>
+      <RuntimeLibrary Condition="'$(Configuration)|$(Platform)'=='Debug|Win32'">MultiThreadedDebug</RuntimeLibrary>
+      <RuntimeLibrary Condition="'$(Configuration)|$(Platform)'=='Debug|x64'">MultiThreadedDebug</RuntimeLibrary>
+      <RuntimeLibrary Condition="'$(Configuration)|$(Platform)'=='Release|Win32'">MultiThreaded</RuntimeLibrary>
+      <RuntimeLibrary Condition="'$(Configuration)|$(Platform)'=='Release|x64'">MultiThreaded</RuntimeLibrary>
     </ClCompile>
     <Link>
       <AdditionalDependencies>version.lib;shlwapi.lib;ws2_32.lib;%(AdditionalDependencies)</AdditionalDependencies>