diff --git a/Utilities/Python/vtkPython.h b/Utilities/Python/vtkPython.h
index 166f24104..79ae1d371 100644
--- a/Utilities/Python/vtkPython.h
+++ b/Utilities/Python/vtkPython.h
@@ -50,7 +50,7 @@
 # include <sys/stat.h>
 # include <time.h>
 # include <wchar.h>
-# undef _DEBUG
+
 # if defined(_MSC_VER)
 #  define _CRT_NOFORCE_MANIFEST 1
 # endif